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. 2016 Nov 15;4:e2702. doi: 10.7717/peerj.2702

Figure 1. Effects of paclitaxel on sodium channel alpha subunits transcript levels in the anterior cingulate cortex (ACC).

Figure 1

Relative mRNA expression of sodium channel alpha subunits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the ACC of BALB/c mice (A) vehicle-treated mice versus untreated mice. Each bar represents the mean ± S.E.M of the values obtained from four untreated mice and four vehicle-treated mice. (B) Relative mRNA expression of sodium channel alpha subunits on day 7 after first administration of the drug or its vehicle. Each bar represents the mean ± S.E.M of the values obtained from 9 to 11 vehicle-treated mice and 12 paclitaxel-treated mice. ** p < 0.01 compared to vehicle-treated mice.