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. Author manuscript; available in PMC: 2016 Nov 22.
Published in final edited form as: Cell. 2016 Jun 2;165(6):1546–1547. doi: 10.1016/j.cell.2016.05.058

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

Darjus F Tschaharganeh, Wen Xue, Diego F Calvisi, Matthias Evert, Tatyana V Michurina, Lukas E Dow, Ana Banito, Sarah F Katz, Edward R Kastenhuber, Susann Weissmueller, Chun-Hao Huang, Andre Lechel, Jesper B Andersen, David Capper, Lars Zender, Thomas Longerich, Grigori Enikolopov, Scott W Lowe *
PMCID: PMC5119474  NIHMSID: NIHMS829563  PMID: 27259155

In the above article, which shows that transcriptional repression of Nestin by p53 restricts cellular plasticity and tumorigenesis in liver cancer, there is a duplicated micrograph panel in Figure 7E. This figure shows the characterization of cholangiocarcinomas arising after delivery of two vector constructs in murine livers (GFP-YAP;shp53 and mCherry-NICD). Panel E documents the expression of GFP (indicating YAP;shp53) and mCherry (indicating NICD), as well as positivity of HNF1b and Nestin staining. Owing to a labeling error, two different photographs of the GFP slide were inadvertently used in the panel, with one incorrectly being labeled as mCherry. A revised version of Figure 7E with the correct micrograph showing mCherry expression is now provided below and supports the original conclusions that expression of GFP and mCherry in the tissue mostly overlaps. We apologize for any confusion that this error may have caused.

Figure 7. Progenitor Cells Can Differentiate to HCC or CC In Vivo.

Figure 7

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