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A. mRNA transcript levels of calcium handling genes (control n=6, sarcomere mutation positive HCM n=20, sarcomere-negative HCM n=10). B. mRNA transcript levels of CaMKII-calcineurin pathway genes. C. Western blot analysis of calcium-handling protein abundance in HCM relative to controls, normalized to GAPDH (control n=6, sarcomere mutation positive HCM n=12, sarcomere-negative HCM n=7). *=p<0.05
