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. 2016 Mar 25;7(26):39497–39510. doi: 10.18632/oncotarget.8347

Figure 8. Effects of paeonol on the activation of the NF-κB signalling pathway in LPS-induced AKI.

Figure 8

BALB/c mice were treated with vehicle or paeonol for 7 days. After the last of administration, all mice except the control group received a single intraperitoneal injection of 10 mg/kg of LPS to induce AKI. Twelve hours after the LPS injection, kidney tissues were collected to measure the phosphorylation of IKKβ (A), IκBα (B) and p65 (C) by Western blot. β-actin was used as a standard control. Results are expressed as fold increase over control group. All data represent the means ± SD from three separate experiments. **p < 0.01, ***p < 0.001 compared to LPS group; ##p < 0.01 and ###p < 0.001 compared to control group.