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Schematic representation of the antimycin biosynthetic gene cluster of S. albus S4. Genes are color coded to indicate their functions. AT, acyltransferase; CCR, crotonyl-CoA carboxylase/reductase. In antimycin A1, R1 is COCH(CH3)CH2CH3 and R2 is (CH2)4CH3. In antimycin A2, R1 is COCH(CH3)2 and R2 is (CH2)4CH3. In antimycin A3, R1 is COCH2CH(CH3)2 and R2 is (CH2)2CH3. In antimycin A4, R1 is COCH(CH3)2 and R2 is (CH2)2CH3.
