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. 1970 Jul;25(4):451–456. doi: 10.1136/thx.25.4.451

Respiratory impairment and airway closure in patients with untreated idiopathic scoliosis

J Bjure 1,2, G Grimby 1,2, J Kasalický 1,2, M Lindh 1,2, A Nachemson 1,2
PMCID: PMC514674  PMID: 5485005

Abstract

Fifty patients aged 11 to 78 years with untreated idiopathic scoliosis were studied. An increased frequency of respiratory impairment was found, especially in patients with a severe degree of scoliosis. Seven patients under 60 years were unable to work and all had thoracic curves exceeding 100°. None of the patients between 20 and 65 years of age was engaged in hard work and 22% had a disability pension, all because of respiratory impairment. A tendency to increased shortness of breath was noted with increasing curves as well as age.

Dynamic and static spirometry was performed and airway closure was studied with the xenon-133 bolus technique. With increasing degrees of scoliosis there was a reduction in all lung volumes. Seventeen of 40 patients showed evidence of airway closure at lung volumes greater than functional residual capacity; 6 of these patients were under 40 years of age, and all had thoracic scoliosis exceeding 90°.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERGLUND E., BIRATH G., BJURE J., GRIMBY G., KJELLMER I., SANDQVIST L., SODERHOLM B. Spirometric studies in normal subjects. I. Forced expirograms in subjects between 7 and 70 years of age. Acta Med Scand. 1963 Feb;173:185–192. [PubMed] [Google Scholar]
  2. BERGOFSKY E. H., TURINO G. M., FISHMAN A. P. Cardiorespiratory failure in kyphoscoliosis. Medicine (Baltimore) 1959 Sep;38:263–317. doi: 10.1097/00005792-195909000-00004. [DOI] [PubMed] [Google Scholar]
  3. BJURE J. Spirometric studies on normal subjects. IV. Ventilatory capacities in healthy children 7-17 years of age. Acta Paediatr. 1963 May;52:232–240. doi: 10.1111/j.1651-2227.1963.tb03775.x. [DOI] [PubMed] [Google Scholar]
  4. Bake B., Bjure J., Grimby G., Milic-Emili J., Nilsson N. J. Regional distribution of inspired gas in supine man. Scand J Respir Dis. 1967;48(3):189–196. [PubMed] [Google Scholar]
  5. COOK C. D., HAMANN J. F. Relation of lung volumes to height in healthy persons between the ages of 5 and 38 years. J Pediatr. 1961 Nov;59:710–714. doi: 10.1016/s0022-3476(61)80007-3. [DOI] [PubMed] [Google Scholar]
  6. Cauchoix J., Duriez J., Ghosez J. P. L'arthrodèse vertébrale pour scoliose par avivement et apposition de greffons cortico-spongieux autogènes. Remarques à propos de l'ostéogenèse de réparation et étude microscopique des pertes de correction post-opératoire. Rev Chir Orthop Reparatrice Appar Mot. 1966 Apr-May;52(3):241–259. [PubMed] [Google Scholar]
  7. DOLLERY C. T., GILLAM P. M., HUGH-JONEP, ZORAB P. A. REGIONAL LUNG FUNCTION IN KYPHOSCOLIOSIS. Thorax. 1965 Mar;20:175–181. doi: 10.1136/thx.20.2.175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. De Coster A., Remacle P. La fonction pulmonaire des cyphoscoliotiques. Acta Orthop Belg. 1967 Jul-Oct;33(4):551–563. [PubMed] [Google Scholar]
  9. DeWald R. L., Lambert C. N., Ray R. D. Internal instrumentation in the treatment of scoliosis. Surg Clin North Am. 1966 Feb;46(1):55–67. doi: 10.1016/s0039-6109(16)37781-7. [DOI] [PubMed] [Google Scholar]
  10. HARRINGTON P. R. THE MANAGEMENT OF SCOLIOSIS BY SPINE INSTRUMENTATION: AN EVALUATION OF MORE THAN 200 CASES. South Med J. 1963 Dec;56:1367–1377. doi: 10.1097/00007611-196312000-00007. [DOI] [PubMed] [Google Scholar]
  11. Holland J., Milic-Emili J., Macklem P. T., Bates D. V. Regional distribution of pulmonary ventilation and perfusion in elderly subjects. J Clin Invest. 1968 Jan;47(1):81–92. doi: 10.1172/JCI105717. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. MANKIN H. J., GRAHAM J. J., SCHACK J. CARDIOPULMONARY FUNCTION IN MILD AND MODERATE IDIOPATHIC SCOLIOSIS. J Bone Joint Surg Am. 1964 Jan;46:53–62. [PubMed] [Google Scholar]
  13. MOE J. H., GUSTILO R. B. TREATMENT OF SCOLIOSIS. RESULTS IN 196 PATIENTS TREATED BY CAST CORRECTION AND FUSION. J Bone Joint Surg Am. 1964 Mar;46:293–312. [PubMed] [Google Scholar]
  14. Nachemson A. A long term follow-up study of non-treated scoliosis. Acta Orthop Scand. 1968;39(4):466–476. doi: 10.3109/17453676808989664. [DOI] [PubMed] [Google Scholar]
  15. Nilsonne U., Lundgren K. D. Long-term prognosis in idiopathic scoliosis. Acta Orthop Scand. 1968;39(4):456–465. doi: 10.3109/17453676808989663. [DOI] [PubMed] [Google Scholar]

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