Table 1.

The 20 most abundant proteins in the corona surrounding TMV-lys in human plasma determined by mass spectrometry.

	Protein name	Protein accession number	Protein molecular weight (Da)	Total Spectrum count
1*	Complement C3 OS=Homo sapiens GN=C3 PE=1 SV=2	CO3_HUMAN	187,149.10	1696
2	Ig kappa chain C region OS=Homo sapiens GN=IGKC PE=1 SV=1	IGKC_HUMAN	11,608.60	577
3	Complement C4-B OS=Homo sapiens GN=C4B PE=1 SV=2	CO4B_HUMAN	192,752.80	387
4*	Complement C4-A OS=Homo sapiens GN=C4A PE=1 SV=2	CO4A_HUMAN	192,786.80	384
5*	Plasminogen OS=Homo sapiens GN=PLG PE=1 SV=2	PLMN_HUMAN	90,567.40	383
6*	Ig mu chain C region OS=Homo sapiens GN=IGHM PE=1 SV=3	IGHM_HUMAN	49,305.70	370
7	Apolipoprotein B-100 OS=Homo sapiens GN=APOB PE=1 SV=2	APOB_HUMAN	515,614.80	316
8	Ig mu heavy chain disease protein OS=Homo sapiens PE=1 SV=1	MUCB_HUMAN	43,056.70	189
9	Serum albumin OS=Homo sapiens GN=ALB PE=1 SV=2	ALBU_HUMAN	69,366.90	117
10	Huntingtin OS=Homo sapiens GN=HTT PE=1 SV=2	HD_HUMAN	347,603.10	90
11	Immunoglobulin lambda-like polypeptide 5 OS=Homo sapiens GN=IGLL5 PE=2 SV=2	IGLL5_HUMAN	23,062.90	86
12	C4b-binding protein alpha chain OS=Homo sapiens GN=C4BPA PE=1 SV=2	C4BPA_HUMAN	67,033.00	84
13	Ig lambda-2 chain C regions OS=Homo sapiens GN=IGLC2 PE=1 SV=1	LAC2_HUMAN	11,293.20	83
14	Fibrinogen alpha chain OS=Homo sapiens GN=FGA PE=1 SV=2	FIBA_HUMAN	94,973.40	64
15	Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=1 SV=3	A2MG_HUMAN	163,289.90	63
16	Ig alpha-1 chain C region OS=Homo sapiens GN=IGHA1 PE=1 SV=2	IGHA1_HUMAN	37,653.80	62
17	Apolipoprotein(a) OS=Homo sapiens GN=LPA PE=1 SV=1	APOA_HUMAN	501,288.90	53
18	Ig gamma-2 chain C region OS=Homo sapiens GN=IGHG2 PE=1 SV=2	IGHG2_HUMAN	35,899.20	51
19	Histidine-rich glycoprotein OS=Homo sapiens GN=HRG PE=1 SV=1	HRG_HUMAN	59,576.60	50
20	Ig gamma-1 chain C region OS=Homo sapiens GN=IGHG1 PE=1 SV=1	IGHG1_HUMAN	36,105.00	47

^*Proteins in the ~70-kDa band distinguishing TMV-lys from TMV-wt.