Table 1.
Study name | ClinicalTrials.gov registration | Treatment weeks | Treatment arms | Randomized patients |
---|---|---|---|---|
Monotherapy | ||||
ACCORD I | NCT00891462 | 12 | Aclidinium 400 μg BID, Aclidinium 200 μg BID, Placebo | 561 |
ACCORD II | NCT01045161 | 12 | Aclidinium 400 μg BID, Aclidinium 200 μg BID, Placebo | 544 |
ATTAIN | NCT01001494 | 24 | Aclidinium 400 μg BID, Aclidinium 200 μg BID, Placebo | 828 |
Combination therapy | ||||
ACLIFORM | NCT01462942 | 24 | Aclidinium/formoterol 400/12 μg BID, Aclidinium/formoterol 400/6 μg BID, Aclidinium 400 μg BID, Formoterol 12 μg BID, Placebo | 1,729 |
AUGMENT | NCT01437397 | 24 | Aclidinium/formoterol 400/12 μg BID, Aclidinium/formoterol 400/6 μg BID, Aclidinium 400 μg BID, Formoterol 12 μg BID, Placebo | 1,692 |
BID, twice-daily.