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. 1976 Feb;17(2):513–524. doi: 10.1128/jvi.17.2.513-524.1976

Persistent reovirus infection of CHO cells resulting in virus resistance.

R Taber, V Alexander, W Whitford
PMCID: PMC515443  PMID: 176428

Abstract

We obtained a persistently infected line of Chinese hamster ovary cells by selection for resistance to reovirus infection. The cells were persistently infected by a population of viruses that were (i) cytopathic for parental chinese hamster ovary cells and (ii) similar to wild-type reovirus in molecular characteristics. The growth rate, plating efficiency, and morphology of the cells were altered. A large majority of the cells in the population were infected. There was no detectable interferon present in the medium. The cells were relatively resistant to a wide range of viruses.

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These references are in PubMed. This may not be the complete list of references from this article.

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