FIG 1.
Pneumocystis murina infection up-regulates production of arginase in vivo. BALB/c mice were infected with 1x107 Pneumocystis (PC) organisms by intratrachael instillation on day 0 and euthanized at post-infection time points. (A) Pneumocystis burden was assessed over time post-infection by microscopically counting organisms in lung digest preparations. (B) Arginase activity in lung digest preparations was determined by measurement of the conversion of arginine into urea and standardized to total protein.