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. 1976 Apr;18(1):167–175. doi: 10.1128/jvi.18.1.167-175.1976

Oligosaccharide moieties of the glycoprotein of vesicular stomatitis virus.

S A Moyer, J M Tsang, P H Atkinson, D F Summers
PMCID: PMC515535  PMID: 176458

Abstract

Vesicular stomatitis virus contains a single structural glycoprotein whose carbohydrate sequences are probably specified by the host cell. The glycopeptides derived by Pronase digestion of the glycoprotein of vesicular stomatitis virus grown in HeLa cells have an average molecular weight of 1,800. There are multiple oligosaccharide chains on the vesicular stomatitis virus glycoprotein with protein-carbohydrate linkages that are cleaved only by strong alkali under reducing conditions, suggesting that they contain asparagine and N-acetylglucosamine. The oligosaccharide moieties, in addition, appear to be heterogeneous in sequence on the basis of their mobilities during electrophoresis and their sensitivities to cleavage by an endoglycosidase. The carbohydrate-peptide linkage region of the major class of oligosaccharides of the vesicular stomatitis virus glycoprotein has the proposed sequence: (see article).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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