Skip to main content
PMC home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1991 May 1;88(9):3967–3971. doi: 10.1073/pnas.88.9.3967

On the association of restriction fragment length polymorphisms across species boundaries.

Y X Fu 1, J Arnold 1
PMCID: PMC51574  PMID: 1673795

Abstract

We study the expected values of gametic-phase disequilibrium in both nuclear and cytonuclear systems in a finite population composed of reproductively isolated subpopulations. Random drift alone within each subpopulation will generate permanent overall non-zero gametic-phase disequilibrium in both a two-locus nuclear system and a cytonuclear system unless the population has an overall initial disequilibrium of zero. We derive formulae for the expected overall disequilibrium when mutation is involved and demonstrate that these values decay to zero at an extremely slow rate compared with the decay of the expected disequilibria within each subpopulation.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arnold J., Asmussen M. A., Avise J. C. An epistatic mating system model can produce permanent cytonuclear disequilibria in a hybrid zone. Proc Natl Acad Sci U S A. 1988 Mar;85(6):1893–1896. doi: 10.1073/pnas.85.6.1893. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Arnold M. L., Shaw D. D., Contreras N. Ribosomal RNA-encoding DNA introgression across a narrow hybrid zone between two subspecies of grasshopper. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3946–3950. doi: 10.1073/pnas.84.11.3946. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Carson H. L. The genetic system, the deme, and the origin of species. Annu Rev Genet. 1987;21:405–423. doi: 10.1146/annurev.ge.21.120187.002201. [DOI] [PubMed] [Google Scholar]
  4. DeSalle R., Giddings L. V. Discordance of nuclear and mitochondrial DNA phylogenies in Hawaiian Drosophila. Proc Natl Acad Sci U S A. 1986 Sep;83(18):6902–6906. doi: 10.1073/pnas.83.18.6902. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Feldman M. W., Christiansen F. B. The effect of population subdivision on two loci without selection. Genet Res. 1974 Oct;24(2):151–162. doi: 10.1017/s0016672300015184. [DOI] [PubMed] [Google Scholar]
  6. Gyllensten U., Wilson A. C. Interspecific mitochondrial DNA transfer and the colonization of Scandinavia by mice. Genet Res. 1987 Feb;49(1):25–29. doi: 10.1017/s0016672300026690. [DOI] [PubMed] [Google Scholar]
  7. Hill W. G., Weir B. S. Variances and covariances of squared linkage disequilibria in finite populations. Theor Popul Biol. 1988 Feb;33(1):54–78. doi: 10.1016/0040-5809(88)90004-4. [DOI] [PubMed] [Google Scholar]
  8. Karlin S., McGregor J. Rates and probabilities of fixation for two locus random mating finite populations without selection. Genetics. 1968 Jan;58(1):141–159. doi: 10.1093/genetics/58.1.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Meagher R. B., McLean M. D., Arnold J. Recombination within a subclass of restriction fragment length polymorphisms may help link classical and molecular genetics. Genetics. 1988 Nov;120(3):809–818. doi: 10.1093/genetics/120.3.809. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nei M., Li W. H. Linkage disequilibrium in subdivided populations. Genetics. 1973 Sep;75(1):213–219. doi: 10.1093/genetics/75.1.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ohta T. Linkage disequilibrium due to random genetic drift in finite subdivided populations. Proc Natl Acad Sci U S A. 1982 Mar;79(6):1940–1944. doi: 10.1073/pnas.79.6.1940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Ohta T. Linkage disequilibrium with the island model. Genetics. 1982 May;101(1):139–155. doi: 10.1093/genetics/101.1.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Tachida H., Cockerham C. C. Analysis of linkage disequilibrium in an island model. Theor Popul Biol. 1986 Apr;29(2):161–197. doi: 10.1016/0040-5809(86)90008-0. [DOI] [PubMed] [Google Scholar]
  14. Watterson G. A. The effect of linkage in a finite random-mating population. Theor Popul Biol. 1970 May;1(1):72–87. doi: 10.1016/0040-5809(70)90042-0. [DOI] [PubMed] [Google Scholar]
  15. Williams J. G., Kubelik A. R., Livak K. J., Rafalski J. A., Tingey S. V. DNA polymorphisms amplified by arbitrary primers are useful as genetic markers. Nucleic Acids Res. 1990 Nov 25;18(22):6531–6535. doi: 10.1093/nar/18.22.6531. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES