Fig. 6. A₁AR or A₃AR is not required for fasting-induced hypothermia.

Baseline Tb (A) and activity (B) in WT (n=6) and Adora1^−/− (n=4) littermates during the light or dark phase. Baseline Tb (C) and activity (D) in WT (n=5) and Adora3^−/− (n=4) littermates during the light or dark phase. Baseline Tb (E) and activity (F) in C57BL/6J (n=6) and Adora1^−/−;Adora3^−/− (n=3) mice. during the light or dark phase. Individual traces of Tb in (G) WT and Adora1^−/− littermates, (H) WT and Adora3^−/− littermates, and (I) C57BL/6J and Adora1^−/−;Adora3^−/− mice during a 24 hour fast. White and black bars indicate light and dark phases, respectively. Data are mean ± SEM.