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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Neuropharmacology. 2016 Nov 30;114:101–113. doi: 10.1016/j.neuropharm.2016.11.026

Fig. 7. Systemic AMP causes hypothermia independent of A1AR, A3AR, and mast cells.

Fig. 7

(A,B) Tb response to AMP (100 mg/kg, i.p.) in C57BL/6J (WT) and Adora1−/− (KO) mice (n=6/group). (C,D) Tb response to AMP (100 mg/kg, i.p.) in C57BL/6J (WT) or Adora3−/− mice (n=4/group). (E,F) Tb response to AMP (100 mg/kg, i.p.) in C57BL/6J and Adora1−/−;Adora3−/− mice (n=5–6/group). (G,H) Tb response to AMP (100 mg/kg, i.p.) in C57BL/6J (WT) or KitW-sh/Wsh mice (n=7–8/group). Data are mean ± SEM; every tenth SEM is shown in A, C, E, and G; * p<0.05, ** p<0.01, *** p<0.001.