Table 3. Effect of concurrent chemotherapy regimens on OS and PFS in esophageal cancer patients receiving chemoradiotherapy.
Model | Sample size | OS | PFS | ||||
---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | ||
Unadjusted | 161 vs. 156 | 0.697 | 0.528-0.920 | 0.011 | 0.784 | 0.599-1.027 | 0.077 |
Propensity score–based models | |||||||
Stratified | 161 vs. 156 | 0.677 | 0.493-0.928 | 0.016 | 0.751 | 0.553-0.945 | 0.036 |
Weighted (IPTW) | 161 vs. 156 | 0.700 | 0.577-0.851 | 0.003 | 0.759 | 0.628-0.918 | 0.014 |
Matcheda | 102 vs.102 | 0.641 | 0.464-0.887 | 0.007 | 0.663 | 0.474-0.928 | 0.016 |
Abbreviations: OS, overall survival; PFS, progression-free survival; HR, hazard ratio; CI, confidence interval; IPTW, inverse probability of treatment weighting.
Adjusted hazard was derived from the Cox proportional hazards marginal structural model.