. Author manuscript; available in PMC: 2017 Dec 27.

Published in final edited form as: Lupus. 2016 Jul 11;26(2):150–162. doi: 10.1177/0961203316655212

Table 2.

List of molecular markers associated with clinical manifestations in SLE or MCTD patients.

Tissue affected	Molecular markers	SLE	MCTD
Skin	BAFF	ø	Nasal ulcers
Skin	IL33	Oral ulcers	Oral ulcers
Joints	IL12p40	Telangiectasia	ø
Joints	IL12p40	Deformity	ø
Blood	C3 level	ø	Anemia
	C4 level	ø	Anemia
	IgM RF ELISA titer	ø	Anemia
	IgG RF ELISA titer	ø	Anemia
	IL33	Leukopenia	ø
	IL33	Lymphopenia	ø
	BAFF	Thrombosis	ø
Heart	IL17A	ø	Pleuritis
Kidney	Urine protein +	Renal disease	ø

Experimental molecular markers are in italics while traditional lab tests are not. All the markers listed are associated with each of the clinical symptoms with a p-value ≤ 0.05 with Bonferroni correction. The empty symbol (ø) represents no significant correlation determined with p ≤ 0.05 after Bonferroni correction. Interleukins are denoted as follow: IL33, IL12p40, BAFF and IL17A). “RF” stands for rheumatoid factor while urine protein + correspond to protein detection in urine samples.