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. 2012 Jun 1;22(6):575–584. doi: 10.1089/thy.2011.0431

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Copyright 2012, Mary Ann Liebert, Inc.

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FIG. 2. — (A) Overall recurrence free survival (RFS) stratified by number of positive nodes in the whole patient cohort. Patients with >3 metastatic nodes have a significantly lower RFS than those with <3 metastatic nodes. (B) Overall RFS stratified by number of positive nodes in patients <45 years old. Patients with >3 metastatic nodes have a significantly lower RFS than those with <3 metastatic nodes. (C) Neck RFS stratified by number of positive nodes in patients >45 years old. Patients with >5 metastatic nodes have a significantly lower RFS than those with ≤5 metastatic nodes. (D) Disease specific survival (DSS) stratified by combined BRAF^V600E mutational and extra-nodal extension (ENE) status in 36 genotyped patients (15 with recurrence and 25 without) matched for various clinico-histopathologic parameters. Patients with extra-nodal extension who are BRAF^V600E positive have a lower DSS than the remaining individuals. +ve, positive nodes.