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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Bioessays. 2016 Oct 24;38(12):1234–1245. doi: 10.1002/bies.201600154

Figure 4.

Figure 4

Planar polarized centriole positioning. A: Centrioles, as basal bodies (BBs) at the apical plane lining the brain ventricle cells, are planar cell polarized, first in radial cells and followed by their differentiation to ependymal cells, where BBs are multiplied generating a multiciliated epithelium. The off-centered distribution in both, radial and ependymal cells, is controlled by the Fz-PCP signaling pathway. B: During Drosophila pupal wing development, centrioles get polarized along the Fz-PCP polarization axis, migrating towards the Fz-Dsh-Fmi-Dgo distal domain. APF: After puparium formation. Protein cartoons are as in Fig. 2 with the Fz-Dsh/Dvl complexes on the right in each cell.