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. 2017 Jan 3;12(1):e0169724. doi: 10.1371/journal.pone.0169724

Correction: Maturation of the Intestinal Epithelial Barrier in Neonatal Rats Coincides with Decreased FcRn Expression, Replacement of Vacuolated Enterocytes and Changed Blimp-1 Expression

Ester Arévalo Sureda, Björn Weström, Stefan G Pierzynowski, Olena Prykhodko
PMCID: PMC5207483  PMID: 28046100

The images for Figs 6, 7 and 8 are incorrectly switched. The image that appears as Fig 6 should be Fig 7, the image that appears as Fig 7 should be Fig 8, and the image that appears as Fig 8 should be Fig 6. The figure captions appear in the correct order.

Fig 6. Expression of mRNA for Fcgrt (FcRn) and Prdm1 (Blimp-1) in the SI of developing rats.

Fig 6

Relative mRNA levels of Fcgrt (a, c) and Prdm1 (b, d) in the proximal and distal SI in 7, 14, 21, 28 and 35 days old rats (n = 4–6) during postnatal development (a, b) and in 17 days old rats treated with PHA or protease at 14–16 days of age (n = 3–4) to induce precocious gut maturation, compared to control rats (c, d). (mean ± SD, a–b and * p < 0.05; *** p < 0.001).

Fig 7. Plasma IgG as an accumulative marker for intestinal macromolecular permeability.

Fig 7

(a) Changes in plasma IgG levels (mg/ml) during postnatal development in suckling rats, 7, 14, and 21 days old and post-weaning rats, 28, 35, 42, 49 and 56 days old (mean ± SD, 10–90% percentile, (boxes), n = 6–10). (b) Decreased plasma IgG levels (mean ± SD, n = 6) in 17 days old rats treated with PHA (* p < 0.05) or protease (non-significant) during 3 days to induce precocious maturation, compared to control rats.

Fig 8. Expression of Blimp-1 in the small intestine during suckling and post-weaning periods.

Fig 8

Immunohistochemical staining of Blimp-1 in representative histological sections (magnification 200x) from the proximal and distal SI in suckling (14d) and post-weaning (28d) rats. Note: Nuclear immunorreactivity of Blimp-1 antibodies in epithelial cells indicated by black arrows; intraepithelial and lamina propria cells–red arrows; crypt cells–green arrows and cells in muscle layer are indicated by blue arrows.

Reference

  • 1.Arévalo Sureda E, Weström B, Pierzynowski SG, Prykhodko O (2016) Maturation of the Intestinal Epithelial Barrier in Neonatal Rats Coincides with Decreased FcRn Expression, Replacement of Vacuolated Enterocytes and Changed Blimp-1 Expression. PLoS ONE 11(10): e0164775 doi: 10.1371/journal.pone.0164775 [DOI] [PMC free article] [PubMed] [Google Scholar]

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