Table 1. frequency of PTEN and INPP4B loss in PDX models of ER+, HER2+ and triple-negative (TN) breast cancer, determined by IHC analysis.

Subtype	N° of PDX	PTEN loss (%)	INPP4B loss (%)	both
ER+	17	4 (24%)	2 (12%)	0
HER2+	8	0	0	0
Triple-negative	42	23 (55%)	32 (76%)	17 (41%)
Total	67	27 (41%)	34 (51%)	17 (26%)