Table 1. Clinical and molecular details of patients.

N.	G.	Age(y)	Rai	LA	IgHVa	ZAP-70b	CD38c	del13q	del17p	del11q	+12	ephrinA4d	Integrin chaine
													αL	β2	α4	β1
1	F	74	low	no	M	neg	neg	-	-	-	+	15.90	11.95	32.06	25.00	21.93
2	M	69	low	no	M	neg	pos	-	-	-	-	30.90	7.37	22.91	9.53	45.00
3	F	91	int	yes	UM	neg	pos	-	-	-	-	20.20	13.32	67.84	63.80	55.24
4	M	59	int	yes	M	neg	pos	-	-	-	-	7.70	13.20	57.45	24.28	50.74
5	M	78	hi	no	M	pos	neg	+	-	-	-	17.80	17.46	30.44	26.00	15.36
6	M	73	hi	yes	M	pos	pos	-	+	-	-	10.70	7.84	23.85	89.00	55.00
7	F	69	hi	yes	M	pos	neg	-	-	-	-	6.30	7.60	14.45	52.00	45.00
8	F	69	low	no	UM	neg	neg	+	-	-	-	36.47	9.92	13.69	19.60	7.58
9	F	78	int	yes	M	neg	neg	-	-	-	-	10.25	8.73	29.23	63.56	35.00
10	F	73	int	yes	M	neg	pos	+	-	-	-	7.83	42.12	65.56	56.78	59.23
11	F	65	hi	yes	UM	pos	neg	+	+	-	-	6.44	5.89	13.56	54.00	33.62
12	M	76	int	yes	UM	pos	neg	+	-	-	-	10.99	10.54	19.81	45.00	53.71
13	F	71	int	yes	M	pos	neg	-	-	-	+	12.62	35.48	56.68	16.53	69.67
14	F	58	hi	yes	M	neg	neg	-	-	-	-	10.46	10.85	21.07	78.00	63.00
15	M	69	int	yes	UM	pos	pos	+	-	-	-	9.63	51.00	54.00	56.00	25.00
16	F	63	int	yes	M	neg	neg.	+	-	-	+	11.25	20.00	23.00	98.00	65.00
17	M	79	int	no	UM	neg	neg	-	-	-	+	56.25	32.00	25.00	12.00	27.00
18	F	62	int	yes	M	neg	n.d.	-	-	-	-	6.98	8.00	68.00	34.00	32.00
19	F	85	int	yes	M	pos	neg	-	-	-	+	4.69	6.00	66.00	65.25	45.00
20	F	77	int	yes	UM	pos	neg	+	-	-	-	26.53	24.00	52.00	65.00	56.00
21	F	88	low	no	M	pos	neg	+	+	+	-	14.35	15.00	36.00	15.00	65.00
22	F	72	low	no	UM	pos	neg	+	-	+	-	62.25	7.00	35.00	15.00	53.00
23	M	75	low	no	UM	pos	neg	+	-	-	-	70.00	18.00	15.00	18.00	21.00
24	F	83	hi	yes	UM	neg	neg	-	-	-	-	18.69	33.00	84.00	70.00	45.00
25	F	58	low	no	M	pos	pos	-	+	-	-	68.00	26.00	29.00	33.00	56.00
26	F	66	low	no	UM	pos	neg	+	-	+	-	25.25	35.00	33.00	35.00	25.00
27	M	73	low	no	M	pos	neg	+	-	-	-	36.25	12.00	38.00	39.00	21.00
28	M	73	int	yes	M	pos	neg	-	-	-	-	14.56	54.00	61.00	66.00	68.00
29	M	68	low	no	UM	pos	pos	+	-	-	-	11.25	9.00	15.00	52.00	23.00
30	M	85	int	yes	UM	pos	pos	+	-	+	-	11.25	36.00	12.00	63.00	33.00

Footnotes:

^aSequences with a germline homology of ≥ 98% were considered as UM;

^{b, c}Determined by flow cytometry (Positivity cut off over isotype stained negative control stainings): ZAP-70, > 25% stained cells; CD38, > 35% stained cells;

^{d, e}Mean Fluorescence Intensity (MFI) determined by flow cytometry.