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FFAR2 deficiency increased the percentage of GR-1+ neutrophils in colon LP, and BRBs significantly increased GR-1+ neutrophil population (A) and the secretion of IL-1β (B), IL-6 (C) and TNF-α (D) in colonic LP in the ApcMin/+ mice but not the ApcMin/+-FFAR2−/− mice. Representative flow cytometry images are presented. Data are expressed as percentages of CD45+ cells. n = 8–30. *P < 0.05.
