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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Brain Res Bull. 2016 Nov 23;128:48–57. doi: 10.1016/j.brainresbull.2016.10.011

Table 2. summarizes the DR neuronal activity of all animals.

Table 2 summarizes the acute and chronic effect of MPD injection on DR neuronal activity from all experimental groups (0.6, 2.5, and 10.0 mg/kg MPD). Inline graphic indicates a significant (p < 0.05) increase in activity following MPD treatment, Inline graphic indicates a significant (p < 0.05) decrease in neuronal activity following treatment, and Inline graphic indicates no change. Acute summarizes the acute effect of MPD; Baseline compares neuronal activity following rechallenge MPD exposure to the initial effect of MPD at ED1.

Population Response direction Acute ED1 Baseline ED10 to ED1 Rechallenge ED10
All Animals
N = 422		 graphic file with name nihms833465t1.jpg 153 (36.2%) 153 (36.3%) 136 (32.2%)
graphic file with name nihms833465t2.jpg 115 (27.3%) 139 (32.9%) 147 (34.8%)
graphic file with name nihms833465t3.jpg 154 (36.5%) 130 (30.8%) 139 (32.9%)