Table 2. The genotype frequency of CYP2D6*10 (100C>T) in controls, HCC, fibrosis and cirrhosis groups.
Genotype | Control | HCC | Fibrosis | Cirrhosis | ||||
---|---|---|---|---|---|---|---|---|
n | Freq (%) | n | Freq (%) | n | Freq (%) | n | Freq (%) | |
C/C | 33 | 31.4 | 35 | 36.5 | 18 | 35.3 | 17 | 37.8 |
C/T | 23 | 21.9 | 45 | 46.9** | 21 | 41.2** | 24 | 53.3** |
T/T | 49 | 46.7 | 16 | 16.7** | 12 | 23.5** | 4 | 8.9**## |
Total | 105 | 96 | 51 | 45 |
P < 0.01 vs. controls.
P < 0.01 vs. fibrosis group.
HCC=hepatocellular carcinoma. n=number. Freq = genotype frequency.