Table 1.
Age (week) | Vrest (mV) | Spike width (ms) | 4th spike interval/1st spike interval | AHP (mV) | N |
---|---|---|---|---|---|
3rd | −69.3 ± 0.45 | 0.70 ± 0.06 | 1.36 ± 0.06 | −13.6 ± 1.6 | 13 |
4th | −70.1 ± 0.25 | 0.71 ± 0.05 | 1.27 ± 0.05 | −14.5 ± 0.9 | 28 |
5th | −69.6 ± 1.26 | 0.90 ± 0.16 | 1.33 ± 0.09 | −13.7 ± 3.2 | 5 |
7th–9th | −70.0 ± 0.65 | 0.75 ± 0.16 | 1.13 ± 0.04 | −11.7 ± 0.7 | 23 |
Firing parameters at the indicated postnatal weeks. For comparison, the ratios between the fourth and the first spike interval in a sample of pyramidal cells from the same mice were 2.3 ± 0.48 (<P28; n = 9), and 2.6 ± 0.39 (>P28; n = 14), at firing frequencies of 10–50 Hz. All differences between age groups were NS. In a representative sample of FS cells (n = 8, from six mice) Rin was 82.2 ± 7 MΩ in the first month, and 55.6 ± 4.5 MΩ after P45 (n = 17, in eight mice). For comparison, Rin for regular-spiking non-pyramidal cells was 98.8 ± 12 MΩ (n = 5, from five mice in the first month of life).