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. 1994 Feb 11;22(3):492–497. doi: 10.1093/nar/22.3.492

DNA stretching on functionalized gold surfaces.

R M Zimmermann 1, E C Cox 1
PMCID: PMC523609  PMID: 8127690

Abstract

We describe a method for anchoring bacteriophage lambda DNA by one end to gold by Au-biotin-streptavidin-biotin-DNA bonds. DNA anchored to a microfabricated Au line could be aligned and stretched in flow and electric fields. The anchor was shown to resist a force of at least 11 pN, a linkage strong enough to allow DNA molecules of chromosome size to be stretched and aligned.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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