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. Author manuscript; available in PMC: 2017 Jan 24.
Published in final edited form as: Nature. 2016 Oct 26;539(7629):433–436. doi: 10.1038/nature20128

Figure 1. Co-expression of upperhand (Uph) and Hand2.

Figure 1

a, The mouse Uph–Hand2 locus. Uph is transcribed 150 bp upstream of Hand2 and contains two Hand2 enhancers (branchial arch enhancer (green) and cardiac enhancer (yellow)) within one of its introns. Bottom, mammalian sequence conservation (blue). b, Section in situ hybridization of E15.5 mouse embryos for either Uph (left) or Hand2 (right). Expression was detected in heart (h), tongue (t) and jaw (j). Scale bars, 1 mm.