Table 2.
Pathologic Characteristics of Adenocarcinoma
| Case | Age | Sex | cTstage | Size (cm) | pTstage | Invasion Depth | LVI | PNI | TME |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 67 | M | TA | 1.5 | Tis | Mucosa | 0 | 0 | |
| 2 | 81 | M | TA | 1.8 | Tis | Mucosa | 0 | 0 | |
| 3 | 74 | F | TA | 2.0 | Tis | Mucosa | 0 | 0 | |
| 4 | 80 | F | TA | 2.6 | Tis | Mucosa | 0 | 0 | |
| 5 | 54 | F | TA | 3.0 | Tis | Mucosa | 0 | 0 | |
| 6 | 56 | M | TA | 3.0 | Tis | Mucosa | 0 | 0 | |
| 7 | 72 | F | TA | 3.5 | Tis | Mucosa | 0 | 0 | |
| 8 | 41 | M | TA | 4.0 | Tis | Mucosa | 0 | 0 | |
| 9 | 72 | M | TA | 4.0 | Tis | Mucosa | 0 | 0 | |
| 10 | 39 | F | TA | 8.0 | Tis | Mucosa | 0 | 0 | |
| 11 | 74 | F | TA | 9.0 | Tis | Mucosa | 0 | 0 | |
| 12 | 50 | F | TA | 3.5 | T1 | Sm1 | 1 | 0 | |
| 13* | 70 | M | TA | 2.5 | T1 | Sm2 | 0 | 0 | Refused |
| 14† | 55 | M | TA | 3.8 | T1 | Sm2 | 0 | 0 | T1N1(1/14) |
| 15‡ | 81 | F | TA | 4.0 | T3 | Subserosa | 0 | 0 | Unfit |
| 16 | 65 | M | Tis | 1.0 | TA | TA | 0 | 0 | |
| 17 | 66 | M | Tis | 1.5 | TA | TA | 0 | 0 | |
| 18 | 54 | F | Tis | 2.5 | TA | TA | 0 | 0 | |
| 19§ | 64 | M | Tis | 0 | Scar tissue | - | 0 | 0 | |
| 20§ | 68 | M | Tis | 1.5 | Scar tissue | - | 0 | 0 | |
| 21 | 75 | M | Tis | 1.3 | Tis | Mucosa | 0 | 0 | |
| 22 | 72 | M | Tis | 3.5 | Tis | Mucosa | 0 | 0 | |
| 23 | 41 | F | Tis | 3.5 | Tis | Mucosa | 0 | 0 | |
| 24 | 85 | M | Tis | 4.5 | Tis | Mucosa | 0 | 0 | |
| 25 | 46 | M | Tis | 5.5 | Tis | Mucosa | 0 | 0 | |
| 26 | 68 | F | Tis | 5.5 | Tis | Mucosa | 0 | 0 | |
| 27 | 71 | M | Tis | 6.5 | Tis | Mucosa | 0 | 0 | |
| 28 | 68 | M | Tis | 8.0 | Tis | Mucosa | 0 | 0 | |
| 29 | 49 | M | Tis | 9.0 | Tis | Mucosa | 0 | 0 | |
| 30‖ | 82 | M | Tis | 0.8 | T1 | Sm1 | 0 | 0 | |
| 31† | 61 | M | Tis | 4.0 | T1 | Sm3 | 0 | 0 | T1N0 |
| 32‡ | 65 | F | Tis | 6.0 | T1 | Sm3 | 0 | 0 | Refused |
| 33† | 67 | M | Tis | 6.0 | T1 | Sm3 | 0 | 0 | T1N0 |
| 34†,¶ | 68 | M | Tis/T1? | 8.5 | T2 | Muscularis | 0 | 0 | T2N0 |
| 35§ | 65 | M | T1 | 0.5 | Scar tissue | - | 0 | 0 | |
| 36§ | 65 | M | T1 | 0 | Scar tissue | - | 0 | 0 | |
| 37§ | 52 | F | T1 | 0 | Scar tissue | - | 0 | 0 | |
| 38 | 76 | F | T1 | 6.0 | TA | TA | 0 | 0 | |
| 39‖ | 82 | M | T1 | 0.6 | T1 | Sm1 | 0 | 0 | |
| 40 | 62 | F | T1 | 1.0 | T1 | Sm1 | 0 | 0 | |
| 41 | 53 | F | T1 | 2.2 | T1 | Sm1 | 0 | 0 | |
| 42# | 64 | M | T1? | 3.0 | T1 | Sm1 | 0 | 0 | |
| 43 | 55 | M | T1 | 4.5 | T1 | Sm1 | 0 | 0 | |
| 44‡ | 70 | M | T1 | 0.5 | T1 | Sm2 | 0 | 0 | Refused |
| 45‡ | 64 | M | T1 | 2.5 | T1 | Sm2 | 0 | 0 | Refused |
| 46‡ | 82 | M | T1 | 2.8 | T1 | Sm2 | 0 | 0 | Unfit |
| 47† | 69 | M | T1/T2? | 2.5 | T1 | Sm3 | 0 | 0 | T1N1(1/12) |
| 48† | 64 | M | T1 | 4.0 | T1 | Sm3 | 0 | 0 | T1N0 |
| 49‡ | 88 | M | T1 | 4.0 | T1 | Sm3 | 1 | 0 | Unfit |
| 50† | 76 | M | T1 | 2.5 | T2 | Muscularis | 0 | 0 | T2N1(1/14) |
| 51†,¶ | 72 | F | T1? | 5.0 | T2 | Muscularis | 0 | 0 | T2N2(4/13) |
| 52‡ | 69 | M | T2 | 2.5 | T1 | Sm2 | 0 | 0 | Unfit |
Included are 9 cases with overstaging and 11 cases with understaging. TA, tubulovillous adenoma; Tis, carcinoma in situ.
*
No Australian Prudential Regulation Authority risk assessment was performed.
†
Patient underwent salvage TME.
‡
Patient was advised to undergo TME but refused TME or was medically unfit to undergo TME.
§
Residual scar tissue after endomucosal resection.
‖
Local recurrence after endoscopic polypectomy.
¶
On pre-operative imaging Endo-US/MRI there was uncertainty about T stage T1/T2. Frozen section during the TEO procedure showed T2, therefore a completion laparoscopic TME was performed immediately.
#
No preoperative biopsy.