Abstract
A strain of Salmonella typimurium LT2 has been isolated which carries an insertion of approximately 700 bp in the gpt gene. The insertion in the gpt gene was shown to be the Salmonella-specific element IS200. The mutation in strain CR1 arose without selection during storage and is only the second phenotypically identified mutation caused by the insertion of IS200.
Full text
PDF![6599](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b04/526853/d9be83afb223/jbacter00165-0435.png)
![6600](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b04/526853/3282ec719c33/jbacter00165-0436.png)
![6601](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b04/526853/f445bb794748/jbacter00165-0437.png)
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Casadesus J., Roth J. R. Absence of insertions among spontaneous mutants of Salmonella typhimurium. Mol Gen Genet. 1989 Apr;216(2-3):210–216. doi: 10.1007/BF00334358. [DOI] [PubMed] [Google Scholar]
- Lam S., Roth J. R. Genetic mapping of IS200 copies in Salmonella typhimurim strain LT2. Genetics. 1983 Dec;105(4):801–811. doi: 10.1093/genetics/105.4.801. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lam S., Roth J. R. IS200: a Salmonella-specific insertion sequence. Cell. 1983 Oct;34(3):951–960. doi: 10.1016/0092-8674(83)90552-4. [DOI] [PubMed] [Google Scholar]
- Lam S., Roth J. R. Structural and functional studies of insertion element IS200. J Mol Biol. 1986 Jan 20;187(2):157–167. doi: 10.1016/0022-2836(86)90225-1. [DOI] [PubMed] [Google Scholar]
- Matsutani S., Ohtsubo H., Maeda Y., Ohtsubo E. Isolation and characterization of IS elements repeated in the bacterial chromosome. J Mol Biol. 1987 Aug 5;196(3):445–455. doi: 10.1016/0022-2836(87)90023-4. [DOI] [PubMed] [Google Scholar]
- O'Reilly C., Turner P. D., Smith-Keary P. F., McConnell D. J. Molecular cloning of genes involved in purine biosynthetic and salvage pathways of Salmonella typhimurium. Mol Gen Genet. 1984;196(1):152–157. doi: 10.1007/BF00334108. [DOI] [PubMed] [Google Scholar]
- Riley M., O'Reilly C., McConnell D. Physical map of Salmonella typhimurium LT2 DNA in the vicinity of the proA gene. J Bacteriol. 1984 Feb;157(2):655–657. doi: 10.1128/jb.157.2.655-657.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463–5467. doi: 10.1073/pnas.74.12.5463. [DOI] [PMC free article] [PubMed] [Google Scholar]