Figure 3.

Bladder weight decreases with treatment. Mice were implanted with 75,000 MB49 cells in the bladder and given 1, 2, 3, or 4 intravesical treatments with CS/IL-12 on days 7, 11, 15, and 18, respectively (n = 5–7 per group). One day after each treatment, the mice were sacrificed and their bladders were removed, weighed (A), and photographed (B) before further processing for analysis. The representative bladders in (B) are placed on a 5.1-mm (0.2 in) grid paper. Error bars indicate mean with SEM. Asterisks indicate differences between PBS and CS/IL-12 treated mice at the indicated time point as determined through Student's t-test: ***p < 0.0005.