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. 1957 Nov 15;43(11):969–975. doi: 10.1073/pnas.43.11.969

HYPOTHESIS FOR THE MECHANISM OF ACTION OF CHYMOTRYPSIN^{^*}

F H Westheimer ¹

PMCID: PMC528565 PMID: 16590123

969

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

BALLS A. K., WOOD H. N. Acetyl chymotrypsin and its reaction with ethanol. J Biol Chem. 1956 Mar;219(1):245–256. [PubMed] [Google Scholar]
BRUICE T. C., SCHMIR G. L. The catalysis of the hydrolysis of p-nitrophenyl acetate by imidazole and its derivatives. Arch Biochem Biophys. 1956 Aug;63(2):484–486. doi: 10.1016/0003-9861(56)90068-6. [DOI] [PubMed] [Google Scholar]
COHEN J. A., JANSZ H. S., OOSTERBAAN R. A. The chemical structure of the reactive group of esterases. Biochim Biophys Acta. 1956 May;20(2):402–403. doi: 10.1016/0006-3002(56)90310-9. [DOI] [PubMed] [Google Scholar]
CUNNINGHAM L. W., BROWN C. S. The influence of pH on the kinetic constants of alpha-chymotrypsin-catalyzed esterolysis. J Biol Chem. 1956 Jul;221(1):287–299. [PubMed] [Google Scholar]
ELLIOTT D. F. A search for specific chemical methods for fission of peptide bonds. I. The N-acyl to O-acyl transformation in the degradation of silk fibroin. Biochem J. 1952 Feb;50(4):542–550. doi: 10.1042/bj0500542. [DOI] [PMC free article] [PubMed] [Google Scholar]
HAMMOND B. R., GUTFREUND H. Two steps in the reaction of chymotrypsin with acetyl-L-phenylalanine ethyl ester. Biochem J. 1955 Oct;61(2):187–189. doi: 10.1042/bj0610187. [DOI] [PMC free article] [PubMed] [Google Scholar]
KAUFMAN S., NEURATH H. Structural requirements of specific inhibitors for alpha-chymotrypsin. J Biol Chem. 1949 Dec;181(2):623–633. [PubMed] [Google Scholar]
PAULING L., COREY R. B., BRANSON H. R. The structure of proteins; two hydrogen-bonded helical configurations of the polypeptide chain. Proc Natl Acad Sci U S A. 1951 Apr;37(4):205–211. doi: 10.1073/pnas.37.4.205. [DOI] [PMC free article] [PubMed] [Google Scholar]
SCHAFFER N. K., SIMET L., HARSHMAN S., ENGLE R. R., DRISKO R. W. Phosphopeptides from acid-hydrolyzed P32-labeled diisopropylphosphoryl chymotrypsin. J Biol Chem. 1957 Mar;225(1):197–206. [PubMed] [Google Scholar]
TURBA F., GUNDLACH G. Aminosäure-Sequenz in der Umgebung des reaktiven Serinrestes im Chymotrypsin-Molekül. Biochem Z. 1955;327(3):186–188. [PubMed] [Google Scholar]

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