Table 5. Genes whose products participate in end joining repair of DSBs.
| Human | Fly | Comments |
|---|---|---|
| XRCC6 | Irbp | Encodes Ku70 |
| XRCC5 | Ku80 | Encodes Ku80 |
| PRKDC | — | Encodes DNA-PKcs. Lost in Diptera |
| DCLRE1C | — | Encodes Artemis. Lost in Diptera |
| POLK | — | Encodes Polκ. Missing in most insects |
| POLL | — | Encodes Polλ. Missing in most insects |
| DNTT | — | Encodes TdT. Missing in most insects |
| LIG4 | Lig4 | |
| XRCC4 | CG3448 | |
| NHEJ1 | CG12728 | NHEJ1 also known as XLF |
| CG32756 | Adjacent paralogs in D. melanogaster species group | |
| POLQ | mus308 | Encodes DNA polymerase θ |