Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 8;9(2):269–284. doi: 10.1080/19420862.2016.1268305

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 AbbVie

PMC Copyright notice

Figure 6. — Systemic and ocular PK profile of ABBV642 in preclinical animals. (A) Mean ( ± SD) serum concentrations of ABBV642 with H435A mutation (solid circle), a control DVD-Ig with H435A mutation (open square) and a control DVD-Ig with wild-type Fc (solid triangle) following a single 5 or 6.7 mg/kg intravenous dose in male B6.Cg-FcRn-276 mice. (B) Mean ( ± SEM) serum concentrations of ABBV642 after a 1 mg/kg intravenous dose in New Zealand White rabbits. (C) Mean ( ± SEM) serum concentrations of ABBV642 after a 0.59 mg ocular dose in New Zealand White rabbits. (D) Mean ( ± SEM) aqueous humor concentrations of ABBV642 after a 0.25 mg ocular dose in New Zealand White rabbits.