Figure 7.

Schematics illustrating (a) fabrication of a ferritin NC, followed by encapsulation of cargo molecules in its cavity through a reversible disassembly/reassembly process. This NC could be disassembled into its subunits at pH equal to 4.0, and then reassembled into the protein NC form at pH=7.5, b) apoferritin NC disassembled to its subunits at pH=11.0, followed by encapsulation of cargo molecules (lutein) and NC assembly at pH=6.0. Chitosan was used to form a polyelectrolyte complex of FCLs via electrostatic interactions with exterior surface of the apoferritin. a and b Reprinted with permission from ref. ¹⁹³ and ¹⁹⁴ Copyright 2016, Royal Society of Chemistry.