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The effect of p38 MAPK inhibitor on pERK. A, Representative confocal images of pERK immunofluorescence in SNs at 60 min after onset of a 5-min pulse of 5-HT, in the absence or presence of the p38 MAPK inhibitor SB203580 (SB). B, Summary data. Compared with the 5-HT alone group, treatment with 5-HT in the presence of SB induced a significant increase in pERK at 60 min after onset of 5-HT. Scale bar, 20 μm. Significant differences are indicated by * for p < 0.05.
