Table 2. Changes in protein expression over time in TBG-RNAi-CK2 treated xenograft tumors.

Protein Detected	Day 5		Day 6		Day 7
	Mean ± SD	p-value	Mean ± SD	p-value	Mean ± SD	p-value
CK2α - cyto	0.54 ± 0.21	0.04	0.73 ± 0.59	0.51	0.90 ± 0.09	0.25
CK2α – nuc	0.75 ± 0.17	0.11	1.23 ± 0.71	0.64	1.09 ± 0.23	0.58
CK2α′ - cyto	0.52 ± 0.31	0.10	0.66 ± 0.45	0.32	0.92 ± 0.20	0.59
CK2α′ - nuc	0.56 ± 0.24	0.11	1.49 ± 1.12	0.53	0.93 ± 0.42	0.80
CK2β – cyto	0.73 ± 0.24	0.20	0.97 ± 0.30	0.90	1.00 ± 0.21	0.99
CK2β - nuc	1.25 ± 0.66	0.59	1.10 ± 0.16	0.54	0.92 ± 0.16	0.51
NFκB p65 – cyto	0.90 ± 0.07	0.47	0.90 ± 0.34	0.67	0.79 ± 0.10	0.05
NFκB p65 – nuc	1.07 ± 0.04	0.84	1.28 ± 0.41	0.39	0.33 ± 0.32	0.05
NFκB p65 p-S529 - nuc	0.38 ± 0.24	0.11	1.21 ± 1.16	0.79	0.52 ± 0.31	0.10
Casp 3FL – cyto	0.68 ± 0.22	0.13	0.80 ± 0.33	0.40	0.64 ± 0.20	0.06
Bcl-xL - cyto	0.60 ± 0.04	0.07	0.84 ± 0.64	0.72	0.43 ± 0.14	0.01
Survivin - nuc	0.91 ± 0.58	0.82	1.01 ± 0.37	0.98	0.41 ± 0.14	0.008

Normalization was performed relative to actin; all TBG-F7 mean quantitation values set as value of 1.

Data presented as mean ± standard deviation (SD), n = 3 for TBG-RNAi-CK2, n = 6 for TBG-F7 days 5 & 6, n = 7 for TBG-F7 day 7.

Casp 3^FL = full length caspase 3 or pro-caspase 3.