Table 1. EGFR expression in pancreatic tissues.
| Groups | EGFR expression levelsa | P valueb | |||
|---|---|---|---|---|---|
| Low | High | ||||
| 0 | 1 | 2 | 3 | ||
| Normal | 79.2% (38/48) |
12.5% (6/48) |
6.2% (3/48) |
2.1% (1/48) |
/ |
| Pancreatitis | 28.6% (2/7) |
42.9% (3/7) |
0 |
28.6% (2/7) |
0.019 |
| Precancerous lesions | 33.3% (7/21) |
28.7% (6/21) |
19% (4/21) |
19% (4/21) |
<0.001 |
| PanIN | 0 |
50% (1/2) |
50% (1/2) |
0 | N |
| Cystadenoma |
25% (1/4) |
25% (1/4) |
0 |
50% (2/4) |
N |
| IPMN |
40% (6/15) |
26.7% (4/15) |
20% (3/15) |
13.3% (2/15) |
0.010 |
| PDAC | 21.4% (22/103) |
12.6% (13/103) |
25.2% (26/103) |
40.8% (42/103) |
<0.001 |
a
EGFR expression levels were classified as 0 (no staining), 1 (light staining), 2 (intermediate staining) or 3 (intense staining).
b
Estimated using the χ2 test compared with normal tissue after dividing the samples into low- and high-expression groups. The low-expression group includes cases with a staining intensity score of 0; the high-expression group includes cases with staining intensity scores of 1-3. N, not detected.