Table 3. List of genes containing deleterious variants that are frequently found in pancreatic patient-derived xenografts (PDXs).

All
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
LAMB3	TPO	MYBPC1	CD101	SPINK5	MOV10L1	C3orf20	RAET1E	TTN	PKD1L2
222	132	132	126	114	110	104	102	98	92
PDX 1
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TPO	ADAM15	MOV10L1	TMEM176B	PASK	DLG1	SLC7A9	RAET1E	PRR5	PAK6
12	12	10	8	8	8	6	6	6	6
PDX 2
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TTN	CPT1B	MYBPC1	LAMB3	ZNF484	TMEM176B	FAM129C	DLG1	ANKRD6	RAET1E
14	14	12	12	8	8	8	8	8	6
PDX 3
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TTN	LAMB3	MOV10L1	ZNF484	TMEM176B	SPINK5	SLC7A9	RAET1E	PCDHGA1	NFATC3
14	12	10	8	8	6	6	6	6	6
PDX 4
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TTN	CPT1B	LAMB3	TMEM176B	PRICKLE1	PASK	CX3CR1	SPINK5	RAET1E	PPP2R4
14	14	12	8	8	8	8	6	6	6
PDX 5
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TTN	TPO	MYBPC1	NUP62	MOV10L1	ZNF484	TMEM176B	TLR10	FAM129C	DLG1
14	12	12	10	10	8	8	8	8	8
PDX 6
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
CAMKK2	NUP62	MOV10L1	ZNF484	PASK	FAM129C	CX3CR1	SPINK5	SP110	SLC7A9
18	10	10	8	8	8	8	6	6	6
PDX 7
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TMEM176B	TLR10	SWT1	FAM129C	SPINK5	SLC7A9	PAK6	LAMB3	GFAP	CD101
8	8	8	8	6	6	6	6	6	6
PDX 8
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TPO	MYBPC1	LAMB3	DLG1	ANKRD6	SPINK5	SP110	RAET1E	PMEL	NRAP
12	12	12	8	8	6	6	6	6	6
PDX 9
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TPO	MYBPC1	LAMB3	NUP62	TLR10	PASK	FAM129C	SPINK5	SLC7A9	RAET1E
12	12	12	10	8	8	8	6	6	6
PDX 10
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
LAMB3	TMEM176B	TLR10	SLC7A9	PPP2R4	NBR1	MUSK	EGFLAM	CD101	CAPG
12	8	8	6	6	6	6	6	6	6
PDX 11
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
CAMKK2	CPT1B	NUP62	MOV10L1	SWT1	PASK	FAM129C	SLC7A9	RAET1E	PRR5
18	14	10	10	8	8	8	6	6	6
PDX 13
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TPO	LAMB3	ADAM15	ZNF484	TLR10	CX3CR1	SP110	SLC7A9	RAET1E	NRAP
12	12	12	8	8	8	6	6	6	6
PDX 14
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
ZNF484	SPINK5	SLC7A9	PPP2R4	NBR1	MUSK	LAMB3	DFNA5	CD101	C3orf20
8	6	6	6	6	6	6	6	6	6
PDX 15
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TTN	CPT1B	LAMB3	ADAM15	NUP62	MOV10L1	PRICKLE1	SPINK5	NBR1	GBP3
14	14	12	12	10	10	8	6	6	6
PDX 17
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
CAMKK2	ZNF484	TMEM176B	SPINK5	PPP2R4	NBR1	MUSK	GFAP	EGFLAM	CHIA
18	8	8	6	6	6	6	6	6	6
PDX 18
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
CAMKK2	MYBPC1	MOV10L1	ZNF484	TLR10	SWT1	PRICKLE1	FAM129C	CX3CR1	SPINK5
18	12	10	8	8	8	8	8	8	6
PDX 19
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
CAMKK2	CPT1B	LAMB3	MOV10L1	ZNF484	TLR10	SPINK5	RAET1E	NRAP	MUSK
18	14	12	10	8	8	6	6	6	6
PDX 20
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
TTN	MYBPC1	LAMB3	ZNF484	TMEM176B	DLG1	SP110	PRR5	PAK6	NBR1
14	12	12	8	8	8	6	6	6	6
HPDE
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
ZZZ3	ZZEF1	ZYX	ZYG11A	ZXDC	ZSWIM6	ZSWIM4	ZSWIM2	ZSCAN5B	ZSCAN5A
0	0	0	0	0	0	0	0	0	0
Pancl
[1]	[2]	[3]	[4]	[5]	[6]	[7]	[8]	[9]	[10]
MOV10L1	TLR10	SWT1	CX3CR1	SPINK5	RAET1E	NBR1	GBP3	CHIA	ZNF229
10	8	8	8	6	6	6	6	6	4