Table 1. Human brain samples information.
PATIENT ID | CLINICAL DIAGNOSIS | ANATOMO-PATHOLOGICAL DIAGNOSIS | GENDER | AGE | TIME POSTMORTEM (hours) |
---|---|---|---|---|---|
CT1 | Control | NFT II + alpha synuclein in olfactory bulb | Male | 64 | 10 |
CT2 | Control | AgD I | Male | 83 | 13 |
CT3 | Control | Cerebral metastasis from lung cancer + NFTI-II | Female | 56 | 14 |
CT4 | Control | Spine thrombosis D + cerebellar ictus +bulb, NFT III | Female | 86 | 4 |
CT5 | Control | iLBD Braak 1, NFT I-II, SVD | Male | 78 | 6 |
CT6 | Control | Minimum AgD I, with patched gliosis | Male | 76 | 11,5 |
SPD1 | PD | LBD Braak 4, ARP I B | Male | 71 | 5 |
SPD2 | PD | LBD Braak 4 + NFT Braak II | Male | 77 | 12 |
SPD3 | PD | LBD Braak 4, ARP II/A, discreet CAA, SVD | Male | 88 | 15 |
SPD4 | PD | LBD 4-5 + ARP IIA | Female | 83 | 4 |
SPD5 | PD | LBD Braak 5 + ARP III B + CAA mod | Male | 74 | 8 |
SPD6 | PD | LBD Braak 5 + AgD | Male | 81 | 5 |
CT= control individuals, SPD= sporadic PD patients LBD: Lewy body disease, stages based on Braak et al. (2003): 1-6. ARP: Alzheimer-type pathology: classification of the neurofibrillary pathology NFT based on Braak et al., (2006) (I-VI) and the neuritic plaques based on CERAD criteria (A-C), CAA amyloid angiopathy. PMD: postmortem delay (in hours). AgD: Argyrophilic grain Disease, SVD Small Vessel Disease.