Table 1. SENP1 overexpression inhibits Mc-induced increases in Sub-G1 PC3 cell populations.

(A) Cell cycle distribution of PC3Vector cells treated with Mc for 24 h
Mc (μM)	Sub-G1 phase (%)	G1 phase (%)	S phase (%)	G2 phase (%)
0	1.69 ±2.43	54.64 ±1.98	29.86 ±2.01	13.81 ±0.37
14	1.23 ±2.52	56.85 ±2.06	27.37 ±1.64	14.55 ±1.82
28	18.86 ±2.12**	46.08 ±1.86	18.77 ±1.97	16.29 ±1.04

(B) Cell cycle distribution of PC3Flag-SENP1 cells treated with Mc for 24 h
Mc (μM)	Sub-G1 phase (%)	G1 phase (%)	S phase (%)	G2 phase (%)
0	0.41 ±2.27	55.44 ±2.18	26.78 ±1.32	17.37 ±1.53
14	0.33 ±2.54	55.59 ±1.6	27.17 ±1.75	16.91 ±2.3
28	11.50 ±2.09**	53.55 ±1.55	17.81 ±1.49	17.14 ±2.4

PC3^Vector and PC3^Flag-SENP1 cells were treated with Mc for 24 h and cell cycle distribution was analyzed using flow cytometry.

^**p < 0.01 compared to control cells.