Skip to main content
. 2016 Jul 18;7(37):59429–59440. doi: 10.18632/oncotarget.10683

Figure 5. NF-кB activation was required for IL-1β induced upregulation of miR-433 in hL-MSC.

Figure 5

A. Levels of miR-433 in the presence of IL-1β were examined in hL-MSC after treatment with either NF-кB inhibitor TPCA-1, p38 inhibitor BIX02188 or JNK inhibitor SP600125, respectively. B. and C. Levels of NF-кB protein (B) and miR-433 (C) in hL-MSC following NF-кB siRNA knock-down were examined by Western blot and RT-PCR, respectively. D. Protein levels of DKK1 in hL-MSC in the presence of IL-1β were examined by Western blot, following treatment with the inhibitors used in (A) or NF-кB siRNA knock-down used in (B). Values were mean ± SD from three independent experiments. ** P < 0.01, ns not significant vs mock or siRNA NC, respectively.