Table 2.
Seed-based analysis
| Seed location | Direction of effect | Cluster index | Cluster size (in voxels) | z max | P value | MNI coordinates (in mm) for the peak location |
Peak region | ||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | |||||||
| Right lingual gyrus | T1D > ND | 9 | 3,009 | 4.67 | <0.00001 | −6 | 64 | 18 | Left frontal pole |
| T1D > ND | 8 | 912 | 3.8 | <0.00001 | −8 | −62 | 34 | Left precuneus | |
| T1D > ND | 7 | 738 | 4.31 | <0.00001 | 10 | −68 | −32 | Right cerebellum | |
| T1D > ND | 6 | 510 | 4.04 | <0.00001 | −8 | −8 | 6 | Left thalamus | |
| T1D > ND | 5 | 393 | 3.86 | 0.000123 | −38 | −56 | −30 | Left cerebellum | |
| T1D > ND | 4 | 311 | 3.82 | 0.000993 | −20 | −16 | −4 | Left pallidum | |
| T1D > ND | 3 | 263 | 4.28 | 0.00367 | −38 | −72 | 52 | Left lateral occipital cortex | |
| T1D > ND | 2 | 258 | 3.44 | 0.00422 | 54 | −56 | 38 | Right angular gyrus | |
| T1D > ND | 1 | 208 | 4.01 | 0.0181 | 18 | −26 | 16 | Right thalamus | |
| ND > T1D | 2 | 287 | 4.34 | 0.00189 | 14 | −18 | 72 | Right precentral gyrus | |
| ND > T1D | 1 | 272 | 3.79 | 0.00286 | −8 | −18 | 56 | Left precentral gyrus | |
| Left prefrontal | T1D > ND | 1 | 387 | 4.22 | 0.000317 | −44 | 4 | −10 | Left planum polare |
ND, subjects without diabetes.