Fig 5 is incorrect. Fig 5B was generated using a statistical software, GraphPad PRISM. The data points in Fig 5B were duplicated by human error, and in addition, the Jurkat-mock with stimulation (+) and without stimulation (-) data were switched. These errors do not influence the results and conclusion of this study. The authors have provided a corrected Fig 5 here.
Fig 5. HBZ inhibits co-localization of PD-1 and SHP-2.
(A) Staining of unstimulated or pervanadate-stimulated Jurkat-mock and Jurkat-HBZ cells was performed using antibodies against PD-1 (green) and SHP-2 (red). All scale bars are 5 μm. Three representative images derived from each sample are shown. Relative fluorescence intensities of PD-1 (green line) and SHP-2 (red line) were obtained on the white dotted line. (B) Co-localization of PD-1 and SHP-2 was judged by Pearson’s correlation coefficient between green and red channels. Each circle represents an individual cell. Statistical analysis was performed using one-way ANOVA with Tukey’s post hoc test.
Reference
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