Table 1.
Quantitative analysis of colocalization of signals in superresolution images and statistical significance of colocalization (related to Figures 4N and 6D, and Figure 4—figure supplement 1).
| voxel colocolization values (%) / p value | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EEA1-SNX6-Homer1b/c | |||||||||||||||
| EEA1 with SNX6 and Homer1b/c | 15.68/ 0.00079 | 12.05/ 0.011 | 17.48/ 0.0086 | 15.18/ 0.0102 | 16.92/ 0.00864 | 16.48/ 0.0127 | 15.33/ 0.0092 | 18.86/ 0.0069 | 15.76/ 0.0089 | 11.96/ 0.0141 | 21.87/ 0.00053 | 15.98/ 0.00065 | 14.58/ 0.0096 | 16.76/ 0.001 | 19.04/ 0.0005 |
| SNX6 with EEA1 and Homer1b/c | 18.56/ 0.00079 | 13.12/ 0.011 | 17.28/ 0.0086 | 13.96/ 0.0102 | 17.44/ 0.00864 | 12.36/ 0.0127 | 15.92/ 0.0092 | 22.64/ 0.0069 | 15.08/ 0.0089 | 14.32/ 0.0141 | 16.34/ 0.00053 | 19.92/ 0.00065 | 15.12/ 0.0096 | 15.44/ 0.001 | 17.56/ 0.0005 |
| Homer1b/c with EEA1 and SNX6 | 14.24/ 0.00079 | 13.16/ 0.011 | 13.64/ 0.0086 | 10.22/ 0.0102 | 16.28/ 0.00864 | 16.84/ 0.0127 | 13.24/ 0.0092 | 13.92/ 0.0069 | 14.84/ 0.0089 | 14.52/ 0.0141 | 18.56/ 0.00053 | 15.36/ 0.00065 | 13.92/ 0.0096 | 13.44/ 0.001 | 17.63/ 0.0005 |
| p150Glued-SNX6-Homer1b/c | |||||||||||||||
| p150Glued with SNX6 and Homer1b/c | 15.63/ 0.004 | 8.13/ 0.01 | 10.06/ 0.015 | 10.06/ 0.0102 | 10.06/ 0.0053 | 10.06/ 0.0047 | 10.06/ 0.003 | 10.06/ 0.0069 | 10.06/ 0.0187 | 7.62/ 0.020< p <0.0460 | 16.38/ 0.0031 | 9.35/ 0.0051 | 8.85/ 0.008< p <0.0340 | 9.97/ 0.00187 | 9.21/ 0.0071 |
| SNX6 with Homer1b/c and p150Glued | 14.57/ 0.004 | 12.89/ 0.01 | 10.41/ 0.015 | 13.02/ 0.0102 | 10.18/ 0.0053 | 12.67/ 0.0047 | 18.49/ 0.003 | 12.33/ 0.0069 | 9.51/ 0.0187 | 9.54/ 0.010< p <0.0250 | 23.55/ 0.0031 | 11.24/ 0.0051 | 9.39/ 0.008< p <0.0320 | 9.18/ 0.00187 | 10.7/ 0.0071 |
| Homer1b/c with SNX6 and p150Glued | 10.32/ 0.004 | 8.27/ 0.01 | 8.33/ 0.015 | 7.15/ 0.0102 | 9.66/ 0.0053 | 9.8/ 0.0047 | 13.16/ 0.003 | 8.49/ 0.0069 | 8.73/ 0.0187 | 8.69/ 0.0120< p <0.0366 | 15.07/ 0.0031 | 9.17/ 0.0051 | 8.24/ 0.0100< p <0.0370 | 8.43/ 0.00187 | 9.03/ 0.0071 |
| DIC-SNX6-Homer1b/c | |||||||||||||||
| DIC with SNX6 and Homer1b/c | 9.21/ 0.0067 | 9.65/ 0.0061 | 20.05/ 0.0049 | 7.9/ 0.007 | 13.41/ 0.006 | 15.25/ 0.0058 | 9.91/ 0.00187 | 10.88/ 0.0072 | 9.41/ 0.0079 | 8.53/ 0.0061 | 10.61/ 0.0071 | 9.64/ 0.0083 | 9.78/ 0.0082 | 10.98/ 0.0086 | 16.12/ 0.0042 |
| SNX6 with DIC and Homer1b/c | 12.00/ 0.0067 | 13.19/ 0.0061 | 14.91/ 0.0049 | 12.02/ 0.007 | 13.07/ 0.006 | 15.49/ 0.0058 | 11.32/ 0.00187 | 9.81/ 0.0072 | 10.1/ 0.0079 | 16.07/ 0.0061 | 10.79/ 0.0071 | 12.48/ 0.0083 | 11.77/ 0.0082 | 9.86/ 0.0086 | 23.11/ 0.0042 |
| Homer1b/c with DIC and SNX6 | 11.43/ 0.0067 | 9.81/ 0.0061 | 13.78/ 0.0049 | 9.82/ 0.007 | 10.71/ 0.006 | 10.86/ 0.0058 | 9.77/ 0.00187 | 9.82/ 0.0072 | 9.22/ 0.0079 | 10.36/ 0.0061 | 9.75/ 0.0071 | 7.87/ 0.0083 | 9.73/ 0.0082 | 10.21/ 0.0086 | 17.17/ 0.0042 |