Gene expression analyses of senescence markers and/or mediators (glb1, serpine1 and rgn) in WT, spns1hi891/hi891 and spns1hi891/hi891;atp6v0cacm/cm (POY and MOY), and atp6v0cacm/cm (Mu; mutant) embryos from intercrosses (inx) of spns1hi891/+fish and spns1hi891/+;atp6v0cacm/+ fish at 72 hpf. Data are mean ±SD (n = 4 samples [3 embryos/sample] per genotype). Error bars represent the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.005; ns, not significant.