| TM4SF1 |
Member of the transmembrane 4 superfamily, which mediate signal transduction events. This protein is highly expressed in different carcinomas. |
[51] |
| ZKSCAN3 |
Transcription activator and promoter of cancer cell progression and/or migration in various tumors and myelomas. |
[52] |
| EREG |
Ligand of the EGF receptor/EGFR and ERBB4. Stimulates cell proliferation. |
[53] |
| MAP3K1 |
Component of a protein kinase signal transduction cascade involved in tumorigenesis. |
[54] |
| PKN2 |
PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in cell migration, cell adhesion and tumor cell invasion. |
[55] |
| AXL |
It transduces signals from the extracellular matrix into the cytoplasm. It is involved in proliferation, migration, resistance to apoptosis and survival. |
[56] |
| FGF5 |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. This gene was identified as an oncogene, which confers transforming potential to mammalian cells. |
[57] |
| THBS1 |
This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions; it plays roles in platelet aggregation, angiogenesis, and tumorigenesis. |
[58] |
| EZR |
This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. |
[59] |
| CPEB4 |
CPEB4 regulates a range of biological processes involved in tumor and progression,. Moreover, CPEB4 is overexpressed in some human tumor types, |
[60] |
| ITGB1 |
ITGB1 has been identified as a potential prognosis biomarker in triple negative breast cancer. |
[61] |
| SUPV3L1 |
Major helicase player in mitochondrial RNA metabolism. May protect cells from apoptosis. |
[62] |
| RYK |
Co-receptor of Wnt proteins. RYK is essential for Wnt-5a-dependent invasiveness in human glioma. |
[63] |
