TABLE 3.
Sensitivity and Specificity of Candidate Biomarkers for PHH for Throughout a Range of Concentrationsa
| APP | sAPPα | L1CAM | ||||||
|---|---|---|---|---|---|---|---|---|
| Conc. | Sens. | Spec. | Conc. | Sens. | Spec. | Conc. | Sens. | Spec. |
| 653.62 | 1.0 | 0.87 | 441.94 | 1.0 | 0.94 | 56.76 | 1.0 | 0.57 |
| 699.67 | 0.91 | 0.89 | 514.43 | 0.91 | 0.95 | 113.33 | 0.91 | 0.89 |
| 823.55 | 0.64 | 0.90 | 688.65 | 0.73 | 0.97 | 125.62 | 0.73 | 0.91 |
aAPP, amyloid precursor protein; Conc., candidate biomarker concentration (in ng/mL); L1CAM, L1 cell adhesion molecule; sAPPα, soluble amyloid precursor protein α; sens., sensitivity; spec., specificity.