Abstract
We examined the termination patterns of single geniculocortical axons in the striate cortex of the tree shrew by using intracellular recording and horseradish peroxidase staining methods. Axons were classified by whether they responded to light onset (ON center) or light offset (OFF center) and whether they were driven by the ipsi- or contralateral eye. Afferents with ON-center responses end in the upper part of layer IV (IVa) whereas afferents with OFF-center responses end in the lower part of layer IV (IVb). Within each tier, axons driven by the ipsilateral and contralateral eye overlap. These results suggest that binocular convergence occurs within layer IV without mixing the information from the ON- and OFF-center pathways and we consider the significance of this arrangement for visual cortical function.
Full text
PDF




Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Blasdel G. G., Fitzpatrick D. Physiological organization of layer 4 in macaque striate cortex. J Neurosci. 1984 Mar;4(3):880–895. doi: 10.1523/JNEUROSCI.04-03-00880.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Casagrande V. A., Harting J. K. Transneuronal transport of tritiated fucose and proline in the visual pathways of tree shrew Tupaia glis. Brain Res. 1975 Oct 17;96(2):367–372. doi: 10.1016/0006-8993(75)90749-0. [DOI] [PubMed] [Google Scholar]
- Conley M., Fitzpatrick D., Diamond I. T. The laminar organization of the lateral geniculate body and the striate cortex in the tree shrew (Tupaia glis). J Neurosci. 1984 Jan;4(1):171–197. doi: 10.1523/JNEUROSCI.04-01-00171.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Conway J. L., Schiller P. H. Laminar organization of tree shrew dorsal lateral geniculate nucleus. J Neurophysiol. 1983 Dec;50(6):1330–1342. doi: 10.1152/jn.1983.50.6.1330. [DOI] [PubMed] [Google Scholar]
- Harting J. K., Diamond I. T., Hall W. C. Anterograde degeneration study of the cortical projections of the lateral geniculate and pulvinar nuclei in the tree shrew (Tupaia glis). J Comp Neurol. 1973 Aug;150(4):393–440. doi: 10.1002/cne.901500403. [DOI] [PubMed] [Google Scholar]
- Hubel D. H. An autoradiographic study of the retino-cortical projections in the tree shrew (Tupaia glis). Brain Res. 1975 Oct 10;96(1):41–50. doi: 10.1016/0006-8993(75)90568-5. [DOI] [PubMed] [Google Scholar]
- Hubel D. H., Wiesel T. N. Ferrier lecture. Functional architecture of macaque monkey visual cortex. Proc R Soc Lond B Biol Sci. 1977 Jul 28;198(1130):1–59. doi: 10.1098/rspb.1977.0085. [DOI] [PubMed] [Google Scholar]
- Hubel D. H., Wiesel T. N. Receptive fields and functional architecture of monkey striate cortex. J Physiol. 1968 Mar;195(1):215–243. doi: 10.1113/jphysiol.1968.sp008455. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Humphrey A. L., Albano J. E., Norton T. T. Organization of ocular dominance in tree shrew striate cortex. Brain Res. 1977 Oct 7;134(2):225–236. doi: 10.1016/0006-8993(77)91069-1. [DOI] [PubMed] [Google Scholar]
- Humphrey A. L., Norton T. T. Topographic organization of the orientation column system in the striate cortex of the tree shrew (Tupaia glis). I. Microelectrode recording. J Comp Neurol. 1980 Aug 1;192(3):531–547. doi: 10.1002/cne.901920311. [DOI] [PubMed] [Google Scholar]
- Kretz R., Rager G., Norton T. T. Laminar organization of ON and OFF regions and ocular dominance in the striate cortex of the tree shrew (Tupaia belangeri). J Comp Neurol. 1986 Sep 1;251(1):135–145. doi: 10.1002/cne.902510110. [DOI] [PubMed] [Google Scholar]
- LeVay S., McConnell S. K., Luskin M. B. Functional organization of primary visual cortex in the mink (Mustela vison), and a comparison with the cat. J Comp Neurol. 1987 Mar 15;257(3):422–441. doi: 10.1002/cne.902570310. [DOI] [PubMed] [Google Scholar]
- Norton T. T., Rager G., Kretz R. ON and OFF regions in layer IV of striate cortex. Brain Res. 1985 Feb 18;327(1-2):319–323. doi: 10.1016/0006-8993(85)91527-6. [DOI] [PubMed] [Google Scholar]
- Palmer L. A., Davis T. L. Receptive-field structure in cat striate cortex. J Neurophysiol. 1981 Aug;46(2):260–276. doi: 10.1152/jn.1981.46.2.260. [DOI] [PubMed] [Google Scholar]
- Schiller P. H. Central connections of the retinal ON and OFF pathways. Nature. 1982 Jun 17;297(5867):580–583. doi: 10.1038/297580a0. [DOI] [PubMed] [Google Scholar]
- Schiller P. H., Finlay B. L., Volman S. F. Quantitative studies of single-cell properties in monkey striate cortex. I. Spatiotemporal organization of receptive fields. J Neurophysiol. 1976 Nov;39(6):1288–1319. doi: 10.1152/jn.1976.39.6.1288. [DOI] [PubMed] [Google Scholar]
- Sherk H., Horton J. C. Receptive field properties in the cat's area 17 in the absence of on-center geniculate input. J Neurosci. 1984 Feb;4(2):381–393. doi: 10.1523/JNEUROSCI.04-02-00381.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sherman S. M., Norton T. T., Casagrande V. A. X- and Y-cells in the dorsal lateral geniculate nucleus of the tree shrew (Tupaia glis). Brain Res. 1975 Jul 25;93(1):152–157. doi: 10.1016/0006-8993(75)90294-2. [DOI] [PubMed] [Google Scholar]