There is an error in Table 1. The values in the last two rows for Animals C7 and C8 in Group 3 were incorrectly omitted. The authors have provided a corrected version here.
Table 1. Reciprocal titres of anti-FMDV antibodies (serotype O) in sera from unvaccinated and rSFV-FMDV vaccinated calves in experiment 1.
Pre-challenge | Post-challenge | |||||
---|---|---|---|---|---|---|
Group | Vaccination and challenge | Animal | PVD 14 | PVD 21 | PVD 27 | PVD 30 |
1 | No vaccination (control) | C1 | - | - | - | 20 |
Needle challenge | C2 | - | - | - | 20 | |
2 | rSFV-FMDV-P1-2A | C3 | - | - | 320 | 320 |
Needle challenge | C4 | - | - | 320 | 320 | |
C5 | - | 5 | 640 | 320 | ||
3 | rSFV-FMDV-P1-2A-mIRES-3C | C6 | 5 | 10 | 320 | 320 |
Needle challenge | C7 | - | - | 320 | 320 | |
C8 | - | - | 320 | 320 |
Calves C3 to C8 were vaccinated with the indicated rSFV-FMDV on PVD 0 and then challenged with FMDV by needle inoculation on PVD 21. To determine the titre, sera collected from calves on PVD 14, 21, 27 and 30 were assayed in the ELISA using 2-fold dilutions starting at 1:5.—indicates negative.
Reference
- 1.Gullberg M, Lohse L, Bøtner A, McInerney GM, Burman A, Jackson T, et al. (2016) A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a “Single-Cycle” Alphavirus Vector and Empty Capsid Particles. PLoS ONE 11(6): e0157435 doi: 10.1371/journal.pone.0157435 [DOI] [PMC free article] [PubMed] [Google Scholar]