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. 2016 Dec 23;129(8):1052–1055. doi: 10.1182/blood-2016-06-722538

Figure 1.

Figure 1.

IgY antibodies in the stool, survival rates, cytokine levels, and histopathology scores. Lethally irradiated B6D2F1 mice received BM cells supplemented with SCs from either syngeneic (Syn; B6D2F1) or allogeneic (Allo; C57BL/6) donors. Thereafter, animals received feed pellets with IgY or control (cont) pellets without IgY. (A) On day 15 after transplantation, stool samples were isolated and the presence of IgY antibodies was determined by enzyme-linked immunosorbent assay. (B) Survival of syngeneic and allogeneic recipients. (C) Cytokine levels on day 28 after alloBMT. Serum cytokine levels were determined on day 28 after alloBMT using cytokine bead assay. (D) Pathology score 28 days after alloBMT. Histopathology scores for small intestine (s. intestine), colon, liver, lung, and skin at day 28 after BMT. Data are presented as mean ± standard error of the mean (SEM); *P < .05, **P < .01. Conc, concentration; n.s, not significant.